Buy Adipotide (FTPP) 5mg

▸Targeting Fat Tissue's Blood Supply

Adipotide (Fat-Targeting Pro-apoptotic Peptide, FTPP) is a chimeric peptide consisting of a targeting sequence that binds prohibitin on the surface of white adipose tissue blood vessels, conjugated to a proapoptotic sequence (KLAKLAK)2 that kills the cell it enters. By selectively binding to and destroying the vasculature of white adipose tissue, Adipotide causes the fat cells it supplies to die from lack of blood flow — a completely novel mechanism for fat loss.

▸Mechanism: Selective Vascular Apoptosis

The targeting peptide (CKGGRAKDC) binds prohibitin expressed on the luminal surface of blood vessels within white adipose tissue — a unique molecular "ZIP code" that distinguishes adipose vasculature from the blood vessels of other tissues. Upon binding, the conjugated (KLAKLAK)2 sequence disrupts mitochondrial membranes, inducing apoptosis specifically in the endothelial cells of fat tissue vasculature. Without blood supply, the surrounding fat cells undergo secondary apoptosis.

▸Primate Research Data

In obese rhesus monkeys, Adipotide treatment produced 11% body weight loss and 27% reduction in visceral fat over four weeks — extraordinary results that represent some of the most dramatic fat loss observed with any single compound in primate research. Adipotide also improved insulin sensitivity, suggesting benefits beyond simple fat mass reduction.