Buy SLU-PP-332 100mg x30 Capsules
ERRα/γ agonist mimicking extreme endurance exercise at the gene expression level
Cheap SLU-PP-332 100mg x30 Capsules — SLU-PP-332 is a synthetic ERRα/γ agonist that activates the transcriptional programs of extreme endurance exercise — dramatically increasing mitochondrial density and fat oxidation capacity.
- Activates ERRα/γ to trigger endurance exercise gene programs
- Increases mitochondrial density and oxidative capacity
- Treated mice ran 70% longer and 45% farther than controls
- Enhances fatty acid oxidation via CPT1 and HADHA upregulation
- Reduces fat mass while preserving lean tissue
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SLU-PP-332: The ERRα/γ Agonist That Activates the Endurance Exercise Transcriptome
70% Endurance Increase
The original research showed SLU-PP-332 increased running distance by 70% in sedentary mice — among the most dramatic exercise performance enhancements observed with any single compound.
Nuclear Receptor Mechanism
Unlike kinase-targeted exercise mimetics, SLU-PP-332 works at the transcription factor level — activating hundreds of exercise-responsive genes simultaneously for comprehensive metabolic reprogramming.
ERRα/γ Selectivity
Selective for ERR orphan receptors rather than estrogen receptors — avoiding the hormonal effects that would accompany non-selective nuclear receptor activation.
Distinct from AICAR
SLU-PP-332's ERR transcriptional mechanism is mechanistically distinct from AICAR's AMPK activation — enabling powerful synergy when both pathways are engaged simultaneously.
The Science Behind SLU-PP-332 100mg x30 Capsules
▸Activating the Endurance Exercise Transcriptome
SLU-PP-332 is a synthetic agonist of estrogen-related receptors alpha and gamma (ERRα/γ) — orphan nuclear receptors that act as master regulators of the transcriptional response to endurance exercise. By directly activating ERRα/γ, SLU-PP-332 triggers the expression of hundreds of genes normally only activated by sustained aerobic training, producing mitochondrial biogenesis, increased fatty acid oxidation capacity, and improved exercise efficiency without physical training.
▸Mechanism: Nuclear Receptor Transcription
ERRα and ERRγ regulate gene networks governing mitochondrial biogenesis (via PGC-1α coactivation), fatty acid oxidation (CPT1, HADHA), oxidative phosphorylation complexes, and muscle fiber type composition. SLU-PP-332 activates these receptors with high potency and ERR selectivity, producing a gene expression pattern that resembles — but exceeds — what occurs during marathon training. Treated mice ran 70% longer and 45% farther than controls.
▸Research Outcomes
The original Washington University study demonstrated dramatic improvements in endurance and metabolic parameters. Subsequent research has confirmed fat mass reduction, improved insulin sensitivity, and potential cardiovascular benefits. As an oral compound with nuclear receptor mechanism, SLU-PP-332 represents a distinct and complementary approach to exercise mimicry compared to AMPK activators like AICAR.
Complete SLU-PP-332 100mg x30 Capsules Benefits
- Activates ERRα/γ to trigger endurance exercise gene programs
- Increases mitochondrial density and oxidative capacity
- Treated mice ran 70% longer and 45% farther than controls
- Enhances fatty acid oxidation via CPT1 and HADHA upregulation
- Reduces fat mass while preserving lean tissue
- Improves insulin sensitivity through metabolic reprogramming
- Oral capsule format for convenient daily dosing
SLU-PP-332 100mg x30 Capsules Dosing Protocol
Dosing:
• Standard: 100mg orally once daily (per research protocols)
• Pre-workout: 100–200mg 1–2 hours before aerobic training
• Cycle: 4–8 weeks; assess response before extending
Note: ERRα/γ agonism produces genuine transcriptional changes — expect 2–4 weeks before full effects manifest
All information on this site is for educational purposes only. Always consult with a qualified healthcare provider before use. COA documentation is available for all products.
SLU-PP-332 100mg x30 Capsules
COA verified · Third-party tested · US domestic shipping
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